Pick the right font!
Some fonts are easier to read than others, and this varies from person to person. So try different fonts and see what works best for you.
At work - my favourites are Calibri, Tahoma and Verdana
At home - I love Comic Sans and Dyslexie (which is FREE from www.dyslexiefont.com)
You can even set one of these fonts as your default in your internet browser (So much joy!!).